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24.10.2021 •
Biology
Assume that for a given gene a mutation creates an allele that functions as a dominant negative. The gene codes for a protein that forms a trimer (3 subunits are needed) within the cell. If at least one of the subunits has the mutant structure the entire protein is inactivated. For a heterozygous individual (one dominant negative allele and one wild-type allele in the same individual), what percent of the trimer present in the cell will be active
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