If two people with sickle cell trait have children, what is thechance that a child will have normal RBCs in both high-and low-oxygen environments? What is the chance that a child will have sickle cell disease? Write the possible genotypes in the Punnettsquare.

See the answer below

Explanation:

The chance that a child from two people with sickle cell trait will have normal RBCs remains the same irrespective of the amount of oxygen in the environment. From the cross:

                  AS    x    AS

            AA    AS    AS    SS

Hence, the chance of having a child with normal RBCs in both high and low-oxygen environments is 1/4 or 25%.

The chance that a child will have sickle cell disease is also 1/4   or 25%.

The possible genotypes in a Punnet's square can be seen in the attached image