In eukaryotes, general transcription factors

A. are required for the expression of specific protein-encoding genes.
B. bind to other proteins or to a sequence element within the promoter called the TATA box.
C. inhibit RNA polymerase binding to the promoter and begin transcribing.
D. usually lead to a high level of transcription even without additional specific transcription factors.
E. bind to sequences just after the start site of transcription.

B

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