Indicate which the following statements are true.
a. During glycolysis, glucose molecules are hydrolysed to yield CO2 and H2O
b. The cleavage of fructose 1,6-bisphosphate by phosphofructokinase yields two molecules of glyceraldehyde 3-phosphate.
c. When subjected to anaerobic conditions, glycolysis in mammalian cells continues and causes a buildup of pyruvate in the cytosol.
d. In the mitochondrial matrix, the pyruvate dehydrogenase complex produces CO2, acetyl-CoA and NADH.
e. Fatty acids can be transported into mitochondria and converted into acetyl-CoA, FADH2 and NADH
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Ответ:
The correct answer is: D
Explanation:
(a) This process does not occur during glycolysis, it occurs after glycolysis since pyruvate is generally accepted to be the last product of glycolysis
(b) Phosphofructokinase does not produce two molecules of glyceraldehyde 3-phosphate but rather produces of one molecule of glyceraldehyde 3-phosphate and dihydroxyacetone phosphate
(c) During anaerobic conditions in mammals, pyruvate is converted to lactate by the enzyme lactate dehydrogenase. It can actually cause the accumulation of lactic acid/lactate in the muscle which causes muscle fatigue but does not cause buildup of pyruvate in the cytosol.
(d) In the fate of pyruvate, the pyruvate dehydrogenase complex produces CO2, acetyl-CoA and NADH in the mitochondrial matrix. The acetyl-coA produced thereof serves as a precursor for the citric acid cycle.
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