Summarize how chromosomal rearrangements may cause some forms of cancer.

Chromosomes, especially homologous chromosomes exchange genetic materials through translocation of their parts in a process called crossing over. If the exchange between the chromosomes is balanced and  preserves the proper complement of genetic material,  then the chances of the probability of mutation are low. However, if this translocation is uneven and disrupts the regulation of genes (such as activate an oncogene or inhibit a tumor suppressor gene probably due to multiple fusions at a single locus) then the chances of cancer are high.

the central limit theorem states that sampling distribution of the sample means approaches a normal distribution as the sample size gets larger — no matter what the shape of the population distribution.