The change in t between pH 6 and pH 7 must involve of a proton in the active site. The best candidate is . The increase in Km at higher pH must involve a change in the binding site. The group involved is probably the at Ile 16, created by the cleavage that activates chymotrypsin. N-terminus
gain
His 57
Asp 102
C-terminus
Ser195
loss

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THC is what gets you high and is very potent in most cases (depending on the marijuana). It also stays in your body depending on how much you smoked or ate. But if you eat marijuana (edibles such as gummies, cookies, rice crispie treats, etc) it’ll actually take longer for the THC to take affect because you consumed it rather than smoking it. It would usually take 30-45min for it to take affect.