Which clinical manifestation is a typical reaction to long-term phenytoin sodium therapy?

A common reaction to long-term phenytoin sodium therapy is the unwanted overgrowth of gingival tissue. Sometimes, careful attention to oral hygiene can help with this side effect, but in extreme cases, surgery is required to remove the excess tissue.

Inherent factors that affect soil pH include climate, mineral content, and soil texture. Natural soil pH reflects the combined effects of the soil-forming factors (parent material, time, relief or topography, climate, and organisms). The pH of newly formed soils is determined by the minerals in the parent material.

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