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skatingflower
14.09.2019 •
Biology
Which end of a new mrna transcript gets a cap during processing in the nucleus?
a. the top
b. the bottom
c. the 3' end
d. the 5' end
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Ответ:
d. the 5' end
Explanation:
Capping is a co-transcriptional modification made to RNA in the nucleus after the first 25–30 nts are incorporated into the nascent transcript, which is synthetized in the 5' ---> 3' direction.
The cap consists of a methylated guanosine nucleotide added to the 5' end of the new mRNA transcript, and is important for several processes, which include:
Protection of the mRNA from the attack of phosphatases and nucleases.Splicing of mRNA in the nucleus.Nuclear export of the mRNA to the cytoplasm.Cap-dependent protein synthesis.Ответ: