Consider the possible thermal [4 4] cycloaddition of two molecules of 1,3-butadiene to generate cycloocta-1,5-diene. Show the HOMO/LUMO interaction which would result, and use this interaction to predict whether the proposed cycloaddition could occur.

It is a specific type of drug resistance.

Antibiotic resistance evolves naturally via natural selection through random mutation, but it could also be engineered by applying an evolutionary stress on a population.

Once such a gene is generated, bacteria can then transfer the genetic information in a horizontal fashion (between individuals) by plasmid exchange.

If a bacterium carries several resistance genes, it is called multiresistant or, informally, a superbug.

Causes Antibiotic resistance can also be introduced artificially into a microorganism through transformation protocols.

Explanation: