How does a mutation in gene affect the order of DNA bases?

The rate would be lower and the concentration of reactants would be lower.

Explanation:

The rate of a chemical reaction depends on the rate constant and the concentration of reactants.

For Ex:

For a reaction experimentally given by A + B > C + D

Rate = k[A][B]

where k is the rate constant

          [A] = concentration of reactant A

          [B] = concentration of reactant B

As the reaction proceeds,the concentration of reactant decrease and concentration of products increase.Rate constant k depends only on temperature and activation energy.Hence it will remain constant throughout the reaction assuming that reaction is carried out at constant temperature and pressure.

Hence rate will depend only on concentration of reactants and hence decrease with decrease in concentration of reactants.