Before reading about the Southern region's economy and lifestyle, do you think it
will be MORE or LESS promising for an immigrant than the North, and why?

D.

Explanation:

The given text is taken from John Winthrop's letter to Sir Nathaniel in 1634. In his letter he described about the rising conflict with the Natives. He described about the deaths inccurred on the Natives because of epidemic of small pox.

Through this letter we can infer that the colonist's attiude towards the Natives was that they felt that had a calling to reach out to the Natives and preach Christianity to them.

This claim is evident in the last line of the letter in which Winthrop writes that the 'Lord has cleared their title.'

So, the correct answer is option D.