Who did this small state or large state compromise guard against tyranny

The American Indians were pushed off their land and relocated to reservations.

Explanation:

The Indian Appropriations Act (1851) had exiled Indians into reservations in the West. For them, life in a reservation was binding, as the lands they were assigned to occupy were usually not viable for farming.

After the Homestead Act of 1862, and up to 1870s, the Army fought the Plains Indian Tribes, and by the end of the 1880s, the Plains Indians had been completely removed from their lands onto the reservations, in order to leave the area open for the Homesteaders to live.