"Commerce" means
activity.

A. Business

B. Border

C. Regulation

Business

Explanation:

To be more precise, Commerce is the act of buying or selling something. This could include all varieties of physical goods or services.  Which why it's mostly correlated with business.

Commercial activities generally can be conducted within two spaces. The first one is a A physical space where  both consumers and sellers could directly interact with one another. The second one is a virtual space where both consumers and sellers utilize technology to conduct the commercial activities without having to meet one another.