Aclient is prescribed olanzapine for the treatment of schizophrenia. the client is voiding three times each night and is always thirsty. based on the adverse effects of olanzapine, what should the nurse suspect is triggering the client's reported polyuria and polydipsia?

Olanzapine is an atypical antipsychotic that is a dopamine-serotonin antagonist wherein it blocks the action of these neurotransmitters to exert its antipsychotic effect. Olanzapine, along with other atypical antipsychotics albeit in a lesser degree, is associated with an increased risk of developing diabetes mellitus in such patients. It was hypothesized that serotonin antagonism may decrease the function of the pancreatic beta cells which secrete insulin. In this case, the nurse should suspect the development of diabetes mellitus because of (1) Olanzapine intake and (2) classic DM symptoms such as polydipsia and polyuria.

Anything that causes mutations is known as mutagens. In genetics, mutagen induced changes are known as mutation. The mutations are categorized under two broader categories; gene mutations and chromosomal mutations.

Explanation:

TypesPhysical mutagens.DNA reactive chemicals.Base analogs.Intercalating agents.Metals.Biological agents.Bacterial.Yeast.