Cody is a teenager with a history of leukemia and an enlarged spleen. today he presents with fairly significant left upper quadrant (luq) pain. on examination of this area, a rough grating noise is heard. what is this sound?

The pain in the upper left quadrant match's with the location of the spleen.

The noise heard is called a splenic rub and can be accompanied with splenic infarction (occlusion of the artery that supplies the spleen). This sound is scratchy, rough and possible to hear when Cody breathes.If he holds his breath, the rub stops.

Explanation:

If the mutation changes the sequence of nucleotides in the DNA, the genotype will change. This change in genotype will give rise to different sequence of amino acids in the polypeptide formed after translation. This different protein may be non-functional or reduced in function, which may ultimately change the phenotype as well.

However, it is important to note that the phenotype may or may not change depending on the type of mutation. If the mutation causes a totally different protein to be synthesized during translation, the phenotype will be greatly affected as well. If the mutation only changes one or two amino acids in the final polypeptide, there might be no visible chanhlge in the phenotype.