For a drug that has an initial plasma concentration of 120 mg/L and a half-life of 3 hours, what would the plasma concentration be 12 hours after the initial concentration of the drug elimination is following first order elimination?

7.5 mg/L

Explanation:

As the drug elimination is following the first order of reaction mechanism so for such reactions the following equation relates the final and initial amount

The values given in the question are

Initial concentration = 120 mg/L

Half life = 3 hours.

Time = 12 hours

Thus, putting the given values in the above equation, we get

Thus, after 12 hours the concentration of the remaining drug will be 7.5 mg/L.

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