Looking at a cell under a microscope, you note that it is prokaryote. how do you know? \
a) the cell lacks cytoplasm
b) the cell lacks a cell membrane
c) the cell lacks a nuceleus
d) the cell lacks genetic material

C) The cell lacks a nucleus.

A eukaryotic cell has a nucleus, but prokaryotic cells do not.

In a reading frame, one base is misplaced for another.

But in a frameshift mutation, a base is added or removed.
Remember, codons are groups of three, and they code for amino acids. In frameshift mutations, another base is added and that completely shifts the frame. Hence, the amino acids are messed up, and so is the protein made from it.