Neutrophils are first line of defense in tissues

Neutrophils represent the first line of defence in response to invading microbes, by phagocytosis of pathogens and/or release of antimicrobial factors contained in specialised granules.

The correct answer is option B) their cells are in direct contact with the environment.

By simple animals we mean unicellular organisms or organisms which have very low grade of organisation. Such organisms do not have three germ layers they either have 2 germ layers or do not have germ layers at all that means that they are comprised of only one cell. Since, they do not have many germ layers in their body their cells are in direct contact with the environment. Their cells can directly obtain nutrients form the environment through the process of diffusion. But, in complex organisms the cells do not obtain nutrients directly from the environment. They have specialized organs and organ systems to accomplish a particular task which increases their efficiency. They have well organized circulatory system which supplies nutrients to the cells/tissues of the body.