Tay-Sachs is a single gene recessive allele. The disease always kills its victims before they can reproduce (and potentially pass on the defective allele). If every Tay-Sachs child dies before their 5th birthday, how does the defective allele get passed on to other babies?

Aerobic glycolysis has a slow rate of ATP production and is predominantly utilized during longer-duration, lower-intensity activities after the phosphagen and anaerobic systems have fatigued. It is important to remember that all three of these systems contribute to the energy needs of the body during physical activity

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