The figure to the right illustrates how a protein might bind to a drug substrate. There are five amino acids in the binding site, and they come into close contact with different functional groups on the drug molecule: 1- Histidine - hydroxyl 2- Aspartate - methyl 3- Glutamine - amine 4- Arginine - carboxylic acid5- Alanine - methyl A. List the number(s) of these pairs that can undergo favorable hydrogen bonding. B. List the number(s) of these pairs that can undergo favorable charge-charge interactions. C. List the number(s) of these pairs that can undergo hydrophobic interactions: D. Suppose you are asked to design a mutation that changes the identity of only one of these amino acids, and also strengthens the binding of the protein to the drug. Please propose a specific mutation and provide your reasoning why it would make the binding stronger. Amino acid #: Type of amino acid after mutation: Reasoning for stronger binding:
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Ответ:
The central nervous system is made up of the brain and spinal cord.
The peripheral nervous system is made up of nerves that branch off from the spinal cord and extend to all parts of the body.
The nervous system comprises the central nervous system, consisting of the brain and spinal cord, and the peripheral nervous system, consisting of the cranial, spinal, and peripheral nerves, together with their motor and sensory endings.