The p53 and Tumor Growth animation demonstrates that mice can develop lymphoma in certain tissues lacking p53. Suppose different p53 gene sequences were added back to the lymphoma in mice. For each of the following, predict whether the lymphoma in the mice would grow or shrink over time.
a. Add a stable p53 that binds better to DNA than wild-type 53.
b. Add p53 with Arg248 altered to alanine.
c. Add p53 that does not bind Zn2+
d. Add a DNA sequence lacking 90% of the p53
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um dude is there a gram or is this for history?
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