An order is given to administer methylprednisolone, an anti-inflammatory drug, by IV at a rate of 36 mg every 30. min . The IV bag contains 125 mg of methylprednisolone in every 2.0 mL . What should the flow rate be in milliliters per minute (mL/min)?

0.0192 mL per min.

Explanation:

IV rate = 36 mg per 30 min.

IV concentration = 125 mg per 2.0 mL

36 mg per 30 min. IV rate = 36/30 = 1.2 mg per min

If 125 mg methylprednisolone is present in 2.0 mL of the IV nag, how many mL would contain 1.2 mg?

      = 2x1.2/125

                        = 0.0192 mL

Therefore, the flow rate of the IV must be 0.0192 mL per min. in order to be able to deliver 36 mg per 30 min.    

M(C₈H₁₀N₄O₂)=194.193 g/mol

w(C)=8A(C)/M(C₈H₁₀N₄O₂)
w(H)=10A(H)/M(C₈H₁₀N₄O₂)
w(N)=4A(N)/(C₈H₁₀N₄O₂)
w(O)=1-{w(C)+w(H)+w(N)}

w(C)=8·12.011/194.193=0.4948
w(H)=10·1.008/194.193=0.0519
w(N)=4·14.007/194.193=0.2885
w(O)=0.1648