For which of the reactions listed below will Gibbs free energy always be. positive?
O A. An exothermic reaction that decreases in entropy
B. An exothermic reaction that increases in entropy
O C. An endothermic reaction that decreases in entropy
D. An endothermic reaction that increases in entropy

I think the answer is: C. An endothermic reaction that decreases in entropy

Explanation:

There are non-polar side chains also present in alanine. And, these non-polar side chains are involved in some hydrophobic interactions in active sideand then it changes into polar amino acid glutamate that will destroy the hydrophobic interaction.

Whereas in glycine there is only hydrogen present in the side chain therefore, it will not affect much.