An agricultural worker experiences difficulty breathing which becomes progressively worse. Tests show inflammation and damage of the lung tissue, but IgE antibodies and granulocytes are in the normal ranges. With which disorder of the immune system are these signs and symptoms consistent?

Well considering that this agricultural worker is in constant contact with crops in the field, the first thing that comes to mind is the possible infection by an opportunistic fungus, a well-known example is infections such as histoplasmosis or paracoccidiodes brasiliensis

We think that man may also be infected with the hiv virus, which would make us better understand how a deep opportunistic mycosis earns an immunological response, although this may or may not occur simultaneously with the reported fungal infection.

Explanation:

What makes me maintain this theory is that opportunistic fungi such as those mentioned that generate deep fungal infections, enter through the airways and mainly affect the lungs, in addition to having a strong relationship with the agricultural sector.

Although I believe that the diagnosis would be certified with a sputum sample, ultrasound, computed tomography and even a possible biopsy of the lung area.