25 × (5 - 2) ÷ 5 - 12 + 24 ÷ 2^3 + 6 + 2^4 ÷ 4 - (1 + 3) + (4^3 - 20 × 3) - 4^2 + 3^5 ÷ 3 ÷ (10 - 1) - 8

Based on the given description above, the correct answer would be the second option: OSTEOPOROSIS. Why osteoporosis? Even though Sally is taking her daily calcium and vitamin D supplements, these wouldn't be properly used up by the body because of the lack of exercise. Exercise helps in the absorption of the essential vitamins and minerals in our body, plus her diet is not appropriate because of high calories and fats. Not having enough absorption of calcium and vitamin D may result in bone disorders which is commonly, osteoporosis. Hope this helps.