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12.06.2020 •
Biology
Chapter 14 Case Study: Genetic dwarfism Seven months pregnant, an expectant mother was under-going a routine ultrasound. While prior tests had been normal, this one showed that the limbs of the fetus were unusually short. The doctor suspected that the baby might have a genetic form of dwarfism called achondroplasia. He told her that the disorder was due to an autosomal dominant mutation and occurred with a frequency of about 1 in 25,000 births. The expectant mother had studied genetics in college and immediately raised several questions. How would you answer two of them? 1. How could her baby have a dominantly inherited disorder if there was no history of this condition on either side of the family? 2. Is the mutation more likely to have come from the mother or the father?
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Ответ:
1.) Achodroplasia is a autosomal dominant disorder, the suspected case suggested that inorder for the parents to produce and offspring with achondroplasia. One parents must have a single mutant gene of achodroplasia to be inherited by his offspring. for this case, It is suggested that the offspring might have developed its own mutant gene as it only affect 1 in 25,000 birth. There is changes of genes during early development.
2.) The mother said that they don't have that history of disorder. again, it's autosomal dominant disorder. one parents must have that kind of disorder so their child can also inherit it. Thus, no of the childs parents is a carrier.
Ответ:
The correct answer is option C which is AUG.
Explanation:AUG is the starting codon present on the mRNA and it codes for the methionine.A codon is the 3 base sequence on the mRNA which is specified for a particular amino acid.There is tRNA for a code which has complementary anti codon for that codon. As the codon binds to particular anticodon, it signal the tRNA for the specific amino acid to attache with poly peptide chain.