Explain how DNA segments can be cut and spliced together to produce recombinant DNA. How do the segments "find" each other and stick together? How is recombinant DNA then cloned to produce multiple copies of the genes?
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Ответ:
Frameshift
Explanation:
Mutations are randomly-occuring changes that occur within the genetic code, DNA due to errors within replication. DNA molecules are long-chain, helical macromolecules that store genetic information They are made up of varying sequences of monomers called nucleotides. which form base pairs and sequences of codons in a reading frame, which gives instructions for protein formation.
Single nucleotide polymorphisms are common, and often result in no changes in amino acids, as silent mutations. Some errors add a random nucleotide (SNP) that results in a premature stop codon, called nonsense mutation. Missense mutations are SNPs that change the sequence of codons resulting in a different amino acid.
Frameshift mutations result from insertions or deletions of nucleotides not divisible by 3. This results in more or less nucleotides needed for a codon and disrupts the reading frame- this results in a different translation of proteins