In the nematode C. elegans, if one inhibits RNA polymerase II (the polymerase required for transcription) in oocytes, such that the fertilized eggs have no access to this polymerase, the embryos develop to the 100 cell stage and then stop dividing. Interestingly, these embryos are able to initiate the movements of gastrulation (which occurs at the 26-cells stage), and segregate the P granules (cytoplasmic determinants) that define the future germ line correctly. This suggests that:
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