How does the mass-energy equation e= mc 2relate to fission?

When an atomic nucleus splits into two or more pieces, the masses of 
the pieces doesn't add up to the mass of the original nucleus. There's 
always some mass missing, and some energy is always radiated from 
the process. 

How much energy ? Exactly what you get when you multiply 

(the amount of mass that's missing) times ( c2 ) .

D

Explanation: