What was a major reason why some muslims believed that ali was the true successor to muhammad? he was the strongest and healthiest of the candidates. he was related to muhammad by blood. he was favored by muhammad's favorite wife, aisha. he was hand-picked by muhammad before his death.

A major reason why some Muslims believed that Ali was the true successor to Muhammad was that he was related to Muhammad by blood.

Explanation:

When Muhammad died in 632, no way of deciding who had to succeed him had been enabled, finally resorting to a traditional system of choice among his most prominent followers. Those who took sides with Ali, Muhammad's cousin and son-in-law, however, felt that he was the only legitimate successor since he had been the closest relative to Muhammad.