During prophase, each pair of chromosomes is attached to each other by the chromatin chromatid centromere dna

Answer is centromere.

Mitosis is a method of cell division in which a cell divides into two identical daughter cells. During mitosis separation duplicated genetic material is done. This division completed in five different phases namely prophase, metaphase, anaphase and telophase.

During prophase, the duplicated pairs of chromosomes get condensed are called sister chromatids. The pair of chromosomes remain joined at a central point called the centromere (a special part of a chromosome where the two identical sister chromatids are attached).

I thought I have answered this question before. Yes emzymes are sensitive to PH and temperature.

Explanation:

if the temperature is above 60 - 70 degree celcius, it looses it's ability to catalyse as such emzymes are kept within the normal body temperature to function effectively. Emzymes are also sensitive to PH changing the pH of its surroundings will also change the shape of the active site of an enzyme and also changing the pH will affect the charges on the amino acid molecules.