Explain how a change in the sequence of nucleotides in a strand of DNA might cause a protein to malfunction

As a result of a change in the sequence of nucleotides in a strand of DNA (Deoxyribonucleic acid), the amino acids also change in the final protein which leads to protein malfunction.

Explanation:

As a result of a change in the sequence of nucleotides in a strand of DNA (Deoxyribonucleic acid), the amino acids also change in the final protein which leads to protein malfunction. If insulin does not work correctly, it may not be able to bind to the insulin receptor.

DNA contains genetic information. It has a double helix structure.

COLLAGEN. The exctracellular protein collagen (making the most abundant extracellular protein in animals) which is required in multicellular organisms to keep the cells together, which is exclusive to animals. Most enzymes responsible for metabolic pathways.