Which of the following describes a function of the endoplasmic reticulum within a cell

protein modification

intracellular transport  

lipid synthesis

For the answer to the question above, one of the functions of endoplasmic reticulum within a cell is the facilitation of protein folding and the transport of synthesized proteins in sacs called cisternae. 
The endoplasmic reticulum contains many ribosomes where proteins are synthesized and this is called the rough endoplasmic reticulum. It is also involved in the packaging of proteins to be transferred out of the cell.
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Adverse effects of topoisomerase inhibitor might include:

•Allergic reaction symptoms, such as fast heart beat and sweating, itching or hives, swelling in the face (lips, tongue, throat) or hands, chest tightness, and wheezing, trouble breathing

• Unexplained fever, chills, or sore throat. Severe nausea, vomiting, or diarrhea with stomach pain, blood in stool or other signs of infection