A. One cause of the Columbian Exchange was the B. One effect of the Columbian Exchange on the Americas was
For example,
C. One effect of the Columbian Exchange of Afro-Eurasia was
For example,

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Causes of European migration: After 1492, the motivations for European migration to the Americas centered around the three G's: God, gold, and glory. Gold refers to the desire to extract natural resources like gold and sugar from the New World.

By far the most dramatic and devastating impact of the Columbian Exchange followed the introduction of new diseases into the Americas. ... Soon after 1492, sailors inadvertently introduced these diseases — including smallpox, measles, mumps, whooping cough, influenza, chicken pox, and typhus — to the Americas.

leo frank was an American factory superintendent who was convicted in 1913 of the murder of a 13 year old employee , Mary Phagan , in Atlanta , Georgia